Published April 2002 | Version v1
Journal article Metadata-only

Development of thiosine-resistant mutant of corynebacterium glutamicum and its potency for lysine production

Creators

  • 1. Gomal Univ., Dera Ismail Khan (Pakistan). Dept. of Chemistry
  • 2. Quaid-i-Azam Univ., Islamabad (Pakistan). Dept. of Biological Sciences

Description

A new strain of corynebacterium glutamicum was isolated and treatment by UV (Ultraviolet) radiation for 30 second at 15 cm from UV germicidal lamp. As a result, thiosine-resistant mutants were isolated and screened for lysine production. The potent mutant produced 22 g/L L. lysine in glucose salt medium, 20 g/L L. lysine in molasses and 15 g/L L. lysine in starch hydrolyzates medium, in stirred tank fermenter at 30 degree centigrade after 4 days. (author)

Additional details

Publishing Information

Journal Title
Science Technology and Development
Journal Volume
21
Journal Issue
2
Journal Page Range
p. 45-48
ISSN
0254-6418

INIS

Country of Publication
Pakistan
Country of Input or Organization
Pakistan
INIS RN
34003613
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BACTERIA; BIOLOGICAL RADIATION EFFECTS; LYSINE; MUTANTS; ULTRAVIOLET RADIATION
Descriptors DEC
AMINO ACIDS; BIOLOGICAL EFFECTS; CARBOXYLIC ACIDS; ELECTROMAGNETIC RADIATION; MICROORGANISMS; ORGANIC ACIDS; ORGANIC COMPOUNDS; RADIATION EFFECTS; RADIATIONS