Published 1992
| Version v1
Report
Automation of the synthesis of [2-carbon-11]thymidine
Description
We have constructed a remote synthesis, using robotics, of [2-11C]thymidine for patient imaging. The total synthesis time is 70 minutes. The typical yield is 13 mCi at EOB or a 13% decay corrected radiochemical yield. This is comparable to the yield we obtain by manual synthesis. The radiochemical purity is typically >99.8%. (author) 11 figs., 1 ref
Additional details
Publishing Information
- Imprint Title
- Targetry '91: Proceedings of the 4. international workshop on targetry and target chemistry
- Imprint Pagination
- 286 p.
- Series
- PSI-Proceedings 92-01.
- Journal Page Range
- p. 210-214.
- ISSN
- 1019-6447
- Report number
- PSI-PROC--92-01
Conference
- Title
- 4. international workshop on targetry and target chemistry.
- Dates
- 9-12 Sep 1991.
- Place
- Villigen (Switzerland).
INIS
- Country of Publication
- Switzerland
- Country of Input or Organization
- Switzerland
- INIS RN
- 24006728
- Subject category
- S07: ISOTOPES AND RADIATION SOURCES;
- Resource subtype / Literary indicator
- Conference, Numerical Data
- Descriptors DEI
- AUTOMATION; CARBON 11; CHEMICAL REACTION YIELD; EXPERIMENTAL DATA; ROBOTS; SYNTHESIS; THYMIDINE
- Descriptors DEC
- AZINES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBON ISOTOPES; DATA; EQUIPMENT; EVEN-ODD NUCLEI; HETEROCYCLIC COMPOUNDS; INFORMATION; ISOTOPES; LIGHT NUCLEI; MINUTES LIVING RADIOISOTOPES; NUCLEI; NUCLEOSIDES; NUCLEOTIDES; NUMERICAL DATA; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PYRIMIDINES; RADIOISOTOPES; RIBOSIDES