Published January 2015 | Version v1
Book Metadata-only

Determination of Biotin: Antibody Molar Ratio

Creators

Description

The determination of the biotinylation yield (number of biotin molecules per molecule of antibody) is important to ensure that the MAb has maintained its immunoreactivity. If the biotinylation of the MAb is carried out with a molar ratio of biotin:antibody ~10:1, then the number of biotins per MAb usually ranges between 6 and 8

Part of:
Yttrium-90 and Rhenium-188 Radiopharmaceuticals for Radionuclide Therapy

Additional details

Identifiers

URL
http://www-pub.iaea.org/MTCD/Publications/PDF/Pub1662web-89688003.pdf; http://www.iaea.org/books;

Publishing Information

Publisher
IAEA
Imprint Place
Vienna (International Atomic Energy Agency (IAEA))
ISBN
978-92-0-103814-2
Imprint Title
Yttrium-90 and Rhenium-188 Radiopharmaceuticals for Radionuclide Therapy
Imprint Pagination
320 p.
Journal Issue
no. 5
Series
IAEA Radioisotopes and Radiopharmaceuticals Series
Journal Page Range
p. 294-295
ISSN
2077-6462

INIS

Country of Publication
International Atomic Energy Agency (IAEA)
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
46044159
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
ANTIBODIES; BIOTIN; BRACHYTHERAPY; LABELLING; MOLECULES; RADIOPHARMACEUTICALS; YIELDS
Descriptors DEC
AZOLES; CARBOXYLIC ACIDS; DRUGS; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; IMIDAZOLES; LABELLED COMPOUNDS; MATERIALS; MEDICINE; NUCLEAR MEDICINE; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANIC SULFUR COMPOUNDS; RADIOACTIVE MATERIALS; RADIOLOGY; RADIOTHERAPY; THERAPY; VITAMIN B GROUP; VITAMINS

Optional Information

Secondary number(s)
STI/PUB--1662