Published 1982 | Version v1
Miscellaneous

The influence of different choleretic drugs on the pharmacokinetics of 99m-Tc-diethyl-IDA

  • 1. Humboldt-Universitaet, Berlin (German Democratic Republic)

Description

The influence of different choleretic drugs on the pharmacokinetics of 99m-Tc-diethyl-IDA was tested in order to further elucidate its handling in the liver. Data from curves generated over the temporal region of patients served as basis for calculations using a 3-compartment-system. Stimulation of bile-acid-independent fraction by Aminophylline in a dose of 0.24 g (n = 8) and 0.48 g (n = 13) intravenously does not alter kinetic data. Stimulation of bile-acid-dependent fraction by dehydrocholate 0.5 g per os accelerates excretion of this radiopharmaceutical. Uptake into the liver is unchanged. (Author)

Additional details

Additional titles

Original title (German)
Einfluss choloretischer Medikamente auf die Kinetik von sup(99m)Tc-diaethyl-IDA

Publishing Information

Publisher
Egermann.
Imprint Place
Vienna (Austria)
ISBN
3-900287-14-7
Imprint Title
Radioactive isotopes in clinic and research
Imprint Pagination
v. 15, pt. 1, 462 p.
Journal Page Range
p. 443-448.
Report number
INIS-mf--8668

Conference

Title
Radioactive isotopes in clinic and research, Gastein international symposium 1982.
Dates
1982.
Place
Bad Gastein (Austria).

Optional Information

Notes
Imprint:Radioaktive Isotope in Klinik und Forschung.;Gasteiner Internationales Symposium 1982.