Published August 2000 | Version v1
Journal article Metadata-only

Study on the pharmacal of 186,188Re-SZ39

Creators

  • 1. Academia Sinica, SH (China). Shanghai Inst. of Nuclear Research
  • 2. Brain Surgery of the Second Hospital Affiliated to Suzhou Medical College, Suzhou (China)

Description

The stability, immunocompetence and cytotoxicity in tumor as well as tumor inhibiting rate of 186,188Re-SZ39 are investigated. The results indicate that 186,188Re-SZ39 is stable in vivo by imaging and the volume of tumor of nude mice reduced obviously. So 186,188Re-SZ39 has a strong cytotoxicity effect against glioma cells and is of good prospect as immuno-radiotherapeutic agent

Additional details

Publishing Information

Journal Title
Journal of Isotopes
Journal Volume
13
Journal Issue
3
Journal Page Range
p. 166-169
ISSN
1000-7512

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
32018464
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
INHIBITION; LABELLED COMPOUNDS; NEOPLASMS; RADIOIMMUNOTHERAPY; RADIOPHARMACEUTICALS; RHENIUM 186; RHENIUM 188; STABILITY; TOXICITY; USES
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; IMMUNOTHERAPY; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; MEDICINE; MINUTES LIVING RADIOISOTOPES; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; RADIOACTIVE MATERIALS; RADIOISOTOPES; RADIOLOGY; RADIOTHERAPY; RHENIUM ISOTOPES; THERAPY; YEARS LIVING RADIOISOTOPES