Fluorescence turn off-on probe (β-cyclodextrin-hydroxyquinoline) for monitoring of Cd²⁺ ions and tetracycline

In this paper, a photoluminescent turn off-on switch probe β-cyclodextrin-hydroxyquinoline (β-CD-HQ) was efficiently applied for detection and measurement of Cd²⁺ ions and detection of tetracycline. The proposed assay has shown an excellent selective fluorescence response toward Cd²⁺ ions over other ions like Al³⁺, Pb²⁺, Zn²⁺, Co²⁺, K⁺, Na⁺ and Sr²⁺. The fluorescence emission intensity of the probe is slightly affected by competing ions. In optimum pH value, 4, the limit of detection and linear concentration range were 0.05 nM and 0.1–1.5 nM, respectively. Additionally, the extraordinary output signal of β-CD-HQ was utilized to investigate the logic behavior of β-CD-HQ in the aqueous media. Accordingly, a solid support logic circuit was made by producing the fluorescence output signal under the stimulation of Cd²⁺ ions and tetracycline as inputs. (paper)