Published February 1, 1990 | Version v1
Journal article Metadata-only

Radioimmunodetection in rhabdo- and leiomyosarcoma with 111In-anti-myosin monoclonal antibody complex

Creators

  • 1. Rotterdam Cancer Institute (Netherland)

Description

In patients with rhabdo- and leiomyosarcoma a radioimmunodiagnostic study was performed with 111In labeled F(ab) fragments of a monoclonal antibody against myosin. Eight patients with rhabdomyosarcoma and 18 patients with leiomyosarcoma were studied. Scanning was performed at 4, 24, and 48 h after administration of 74 MBeq of the antibody complex. A high uptake with a tumor:background ratio of 10:1 was observed in several patients with rhabdomyosarcoma but the results were less accurate in leiomyosarcoma

Additional details

Publishing Information

Journal Title
Cancer Research
Journal Volume
50
Series
Cancer Res.
Journal Page Range
955s-957s
ISSN
0008-5472
CODEN
CNREA

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
21053518
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ACCURACY; ANTIGENS; DIAGNOSIS; INDIUM 111; MONOCLONAL ANTIBODIES; MYOSIN; PATIENTS; RADIOIMMUNODETECTION; SARCOMAS
Descriptors DEC
ANTIBODIES; BETA DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; GLOBULINS; INDIUM ISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; PROTEINS; RADIOISOTOPES; TRACER TECHNIQUES