Use of the scanditronix MC40 cyclotron of the JRC (EC) for FDG production in compliance with the European GMP
Creators
- 1. European Commission, Ispra (Italy). Joint Research Centre, Inst. for Health and Consumer Protection
- 2. Amersham Health, Saluggia (Italy)
Description
The Scanditronix MC40 Cyclotron of the Joint Research Centre (JRC) of the European Commission (Ispra site), installed in 1982, is used for materials research and for production of radioisotopes for medical applications (diagnosis and therapy). Regarding radioisotope production, the main ongoing projects are [18F]Fludeoxyglucose (FDG) production in collaboration with Amersham Health (Italy) and studies of methods for production of 64Cu [1], 211At [2] and 225Ac [3]. The present paper is focused on the use of MC 40 Cyclotron for routine FDG production in compliance with the European Good Manufacturing Practices (GMP) guidelines. The main components of the facility are described - the cyclotron, the target and the production and quality control laboratories. (author)
Additional details
Publishing Information
- Imprint Title
- Cyclotrons and their applications 2004. Proceedings of the seventeenth international conference
- Imprint Pagination
- 707 p.
- Journal Page Range
- p. 25-27
Conference
- Title
- 17. international conference on cyclotrons and their applications 2004
- Dates
- 18-22 Oct 2004
- Place
- Tokyo (Japan)
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 36111970
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Conference, Non-conventional Literature
- Descriptors DEI
- ACCELERATOR FACILITIES; CYCLOTRONS; FLUORINE 18; FLUORODEOXYGLUCOSE; ISOTOPE PRODUCTION; QUALITY CONTROL; RADIOPHARMACEUTICALS; STERILIZATION; SYNTHESIS; TARGETS; WATER
- Descriptors DEC
- ACCELERATORS; ANTIMETABOLITES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CONTROL; CYCLIC ACCELERATORS; DRUGS; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; HYDROGEN COMPOUNDS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; NANOSECONDS LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; OXYGEN COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES