The effect of dietary sulfur on the metabolism of long chain polyunsaturated fatty acids
Description
The effect of methionine-supplemented diet on the metabolism of polyunsaturated fatty acids was studied by comparing results of control and cysteine-supplemented diets in rats. Adult Sprague-Dawley rats were fed for a period of 17 days one of the following diets: control, cysteine-supplemented, and/or methionine-supplemented. On the last day of the feeding period, the rats were administered either [1-14C] arachidonic acid (AA) or [1-14C] eicosapentaenoic acid (EPA) by stomach tube five hours before sacrificing. The cyclooxygenase activity in liver microsomes, the apparent Km of the fatty acyl-CoA synthetase in liver and brain homogenates, and the incorporation of polyunsaturated fatty acids into the phosphatidylinositol fraction of brain, heat, lung, spleen, and kidney tissues were analyzed
Availability note (English)
University Microfilms, PO Box 1764, Ann Arbor, MI 48106, Order No.89-04,037.Additional details
Publishing Information
- Publisher
- Univ. of Tennessee.
- Imprint Place
- Knoxville, TN (USA)
- Imprint Pagination
- 104 p.
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 21052983
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Resource subtype / Literary indicator
- Thesis, Non-conventional Literature
- Descriptors DEI
- ARACHIDONIC ACID; BIOLOGICAL EFFECTS; CARBON 14 COMPOUNDS; CARBOXYLIC ACIDS; CYSTEINE; DIET; EICOSANOIC ACID; ENZYME ACTIVITY; LIGASES; METABOLISM; METHIONINE; MICROSOMES; OXYGENASES; RATS; TISSUE DISTRIBUTION; TRACER TECHNIQUES
- Descriptors DEC
- AMINO ACIDS; ANIMALS; CARBON COMPOUNDS; DISTRIBUTION; DRUGS; ENZYMES; ISOTOPE APPLICATIONS; LIPOTROPIC FACTORS; MAMMALS; MONOCARBOXYLIC ACIDS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC SULFUR COMPOUNDS; OXIDOREDUCTASES; RODENTS; THIOLS; VERTEBRATES