Published October 1993 | Version v1
Journal article Metadata-only

Synthesis of D,L-[2-15N,5-13C]glutamic acid

Creators

  • 1. Northwestern Univ., Evanston, IL (United States). Dept. of Biochemistry, Molecular Biology and Cell Biology

Description

A one-pot procedure is described for the synthesis of D,L-[15N,13C]glutamic acid from 2-bromo-4-butyrolactone utilizing potassium 15N-phthalimide and potassium 13C-cyanide as label sources. Following a two column purification procedure, the final product is obtained in 38% yield based on the equimolar label sources. (author)

Additional details

Publishing Information

Journal Title
Journal of Labelled Compounds and Radiopharmaceuticals
Journal Volume
33
Journal Issue
10
Journal Page Range
p. 913-919.
ISSN
0362-4803
CODEN
JLCRD4

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
25024803
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
CARBON 13; CHEMICAL PREPARATION; CYANIDES; GLUTAMIC ACID; IMIDES; LABELLED COMPOUNDS; LABELLING; LACTONES; NITROGEN 15; POTASSIUM COMPOUNDS
Descriptors DEC
ALKALI METAL COMPOUNDS; AMINO ACIDS; CARBON ISOTOPES; CARBOXYLIC ACIDS; ESTERS; EVEN-ODD NUCLEI; HETEROCYCLIC COMPOUNDS; ISOTOPES; LIGHT NUCLEI; NITROGEN ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; STABLE ISOTOPES; SYNTHESIS