Study of the enterotoxigenicity of enterobacteria and their resistance to antibiotics in postirradiation abacteriosis

Qualitative and quantitative composition of Enterobacteriaceal family was studied and the percentage of enterotoxigenic and antibiotic resistant strains was determined in the large intestine cavity of intact mice of CBA line as well as in the cavity and wall of the small intestine of those animals on the 7 day after γ-irradiation (900 R). It was ascertained that postirradiation abacteriosis was characterized by the penetration in quantity of Esub(coli,Pr. morganii) into the small intestine and by the emergence in the small intestine of non-determinable in the intestinal tract intact animals: Pr. vulgaris, Pr. mirabilis, Pr. rettgeri, Ent. aerogenes, Ent. cloacae, Ent. hafniae, Citrobacter freundii, Providencia alcalifaciens; all revealed representatives of enterobacteria were capable of establishing associative bond with the mucous membrane of the intestine. Enterobacteria synthesizing resistant to antibiotics enterotoxins were revealed in quantity in the wall and lumen of the small intestine of irradiated mice