Radiotherapy response and related clinicopathological factors of patients with cervical cancer

The incidence of cervical cancer was still high in RSCM, and most patients exhibited advanced stage disease. For approximately 20–50% of these patients, radiotherapy did not achieve local tumor control. Achieving complete response and eradication of locoregional tumors in patients with cervical cancer should improve survival rates. Therefore, the purpose of this study was to determine the radiotherapy response, and related clinic-pathologic characteristics of patients with cervical cancer at our hospital. We used secondary data from 123 patients with stage IIA-IIIB cervical cancer who underwent radiation therapy at our hospital from January, 2014 to December, 2015. We recorded age, body mass index, blood pressure, hemoglobin, blood leucocyte count, serum albumin, largest tumor diameter FIGO staging, and pathologic characteristics for each patient. During radiation until 3 months post radiation, we also noted any gastrointestinal, genitourinary, and hematologic side effects. Our results indicate that acute side effects were generally tolerable during and three months post radiation therapy. The clinicopathologic characteristic that significantly related to complete response was largest tumor diameter. (paper)