New model for an epoxy-based brachytherapy source to be used in spinal cancer treatment
Creators
- 1. Laboratório de Produção de Fontes para Radioterapia, Instituto de Pesquisas Energéticas e Nucleares (IPEN / CNEN - SP), Universidade de São Paulo, Av. Professor Lineu Prestes 2242, São Paulo, SP, 05508-000 (Brazil)
Description
Highlights: • Cold methodology for radiation source fabrication in epoxy resin is described. • Two molds were tested: commercial silicone and Teflon (better agreement). • Average dose by Monte-Carlo simulation for the regular plaque was 16.44 cGy/s. • 0.01 cm thickness variation led to differences of up to 12% in the dose rate. The present work described the cold fabrication of a P-32 radioactive source to be used in CNS cancer using epoxy resin. The epoxy plaque fabricated with Teflon mold presented better agreement. MCNP simulation evaluated the radiation dose. Special attention was given to factors that can impact dose distribution. Average dose was 16.44 ± 2.89% cGy/s. Differences of less than 0.01 cm in thickness within the plaque lead to differences of up to 12% in the dose rate.
Availability note (English)
Available from http://dx.doi.org/10.1016/j.apradiso.2021.109952Additional details
Identifiers
- DOI
- 10.1016/j.apradiso.2021.109952;
- PII
- S0969804321003493;
Publishing Information
- Journal Title
- Applied Radiation and Isotopes
- Journal Volume
- 178
- Journal Page Range
- vp.
- ISSN
- 0969-8043
- CODEN
- ARISEF
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 54073061
- Subject category
- S07: ISOTOPES AND RADIATION SOURCES;
- Descriptors DEI
- BRACHYTHERAPY; COMPUTERIZED SIMULATION; DOSE RATES; EPOXIDES; MONTE CARLO METHOD; NEOPLASMS; PHOSPHORUS 32; RADIATION DOSES; RADIATION SOURCES; RESINS; SILICONES
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CALCULATION METHODS; DAYS LIVING RADIOISOTOPES; DISEASES; DOSES; ISOTOPES; LIGHT NUCLEI; MEDICINE; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANIC OXYGEN COMPOUNDS; ORGANIC POLYMERS; ORGANIC SILICON COMPOUNDS; PETROCHEMICALS; PETROLEUM PRODUCTS; PHOSPHORUS ISOTOPES; POLYMERS; RADIOISOTOPES; RADIOLOGY; RADIOTHERAPY; SILOXANES; SIMULATION; THERAPY
Optional Information
- Copyright
- Copyright (c) 2021 Elsevier Ltd. All rights reserved.