Published October 1980 | Version v1
Journal article

Iodine contrast medium sensitizes cultured mammalian cells to x rays but not to γ rays

  • 1. National Inst. of Radiological Sciences, Chiba-shi, Japan

Description

The influence of an iodine contrast medium on several responses to radiation was examined in mammalian cells in culture (L5178Y). The presence of the medium at the time of irradiation enhanced cell killing, frequency of micronuclei, and yield of DNA single-strand breaks induced by x rays, depending on the concentration used, whereas no such effect was found with γ rays. It was concluded that the contrast medium sensitizes mammalian cells in culture primarily by means of the photoelectric effect, thereby increasing the absorbed dose of x rays in the cells

Additional details

Publishing Information

Journal Title
Radiat. Res.
Journal Volume
84
Journal Issue
1
Series
Radiat. Res.
Journal Page Range
144-148
ISSN
0033-7587