Published November 1997 | Version v1
Journal article Metadata-only

Comparison of radiation effects in human hepatoma cell line SMMC-7721 irradiated by 30 MeV/u 40Ar15+ and 60Co γ-ray

Creators

  • 1. Chinese Academy of Sciences, Lanzhou (China). Inst. of Modern Physics
  • 2. Lanzhou Univ. (China). Dept. of Biology

Description

Radiation effects of cultured human hepatoma cell line SMMC-7721 irradiated by heavy ion 30 MeV/u 40Ar15+ and 60Co γ-ray are compared. Process of the cell death after irradiation is studied by observing the alive cells and the fixed cells. The results show that both heavy ion and γ-ray can cause serious damage to the cells, and affect the cell survival fraction. Meanwhile, the killing effect on cells by heavy ion is stronger than that by γ-ray. At the 48th hour after treatment, the relative biological effectiveness of heavy ion is 1.5 based on cell survival of 50%

Additional details

Publishing Information

Journal Title
Journal of Radiation Research and Radiation Processing
Journal Volume
15
Journal Issue
4
Journal Page Range
p. 249-252.
ISSN
1000-3436
CODEN
FYYXEA

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
29007063
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
ARGON IONS; BIOLOGICAL RADIATION EFFECTS; CELL CULTURES; COBALT 60; GAMMA RADIATION; HEAVY IONS; HEPATOMAS; LIVER CELLS; MORTALITY; PATIENTS; RADIOSENSITIVITY
Descriptors DEC
ANIMAL CELLS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; CARCINOMAS; CHARGED PARTICLES; COBALT ISOTOPES; DISEASES; ELECTROMAGNETIC RADIATION; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; IONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MAN; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEI; ODD-ODD NUCLEI; PRIMATES; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; SOMATIC CELLS; VERTEBRATES; YEARS LIVING RADIOISOTOPES