Published April 1986 | Version v1
Journal article Metadata-only

Thyroid gland function during the systemic graft versus host reaction

Creators

  • 1. Smolensk Medical Institute

Description

The aims of the present investigation were as follows: to determine the level of thyroid hormones and thyrotrophin (TSH) at various times after induction of graft versus host reaction (GVHR); to study the degree of 125 I uptake by thyroid gland tissue at the same times of the GVHR, and to determine correlation between the hormone levels and weight of the gland in the animals and also the body weight of the recipients. Serum levels of tri-iodothyronine (T3), thyroxine (T4), and TSH were determined by radioimmunoassay. 125 /SUB I/ was injected intraperitoneally in a dose of 3-4 microCi/100 g body weight. During the development of a systemic GVHR marked inhibition of thyroid function was discovered

Additional details

Publishing Information

Journal Title
Bull. Exp. Biol. Med. (Engl. Transl.)
Journal Volume
100
Journal Issue
11
Series
Bull. Exp. Biol. Med. (Engl. Transl.).
Journal Page Range
1564-1565
ISSN
0007-4888
CODEN
BEXBA

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
18035950
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
BIOLOGICAL FUNCTIONS; CORRELATIONS; GRAFT-HOST REACTION; IMMUNE SERUMS; INTRAPERITONEAL INJECTION; IODINE 125; LABELLED COMPOUNDS; RADIOIMMUNOASSAY; SCINTILLATION COUNTING; SPLEEN CELLS; THYROID; THYROXINE; TRIIODOTHYRONINE; TSH; UPTAKE; WEIGHT
Descriptors DEC
AMINO ACIDS; ANIMAL CELLS; BETA DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; ENDOCRINE GLANDS; GLANDS; HORMONES; INJECTION; INTAKE; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IODINE ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANS; PEPTIDE HORMONES; PITUITARY HORMONES; RADIOISOTOPES; SOMATIC CELLS; THYROID HORMONES; TRACER TECHNIQUES

Optional Information

Notes
Cover-to-cover translation of Byulleten' Ehksperimental'noj Biologii i Meditsiny (USSR).