Published January 9, 2007 | Version v1
Journal article

Counting colonies of clonogenic assays by using densitometric software

  • 1. CCC Tübingen, Department of Radiation Oncology, Hoppe-Seyler-Str. 3, 72076 Tübingen (Germany)
  • 2. Bureau for Technique and Documentation, Paracelsusstr. 21, 70599 Stuttgart (Germany)

Description

Clonogenic assays are a useful tool to test whether a given cancer therapy can reduce the clonogenic survival of tumour cells. A colony is defined as a cluster of at least 50 cells which can often only be determined microscopically. The process of counting colonies is very extensive work and so we developed software that is able to count the colonies automatically from scanned flasks. This software is made freely available by us with a detailed description how to use and install the necessary features

Availability note (English)

Available from http://dx.doi.org/10.1186/1748-717X-2-4; Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770926

Additional details

Publishing Information

Journal Title
Radiation Oncology (Online)
Journal Volume
2
Journal Page Range
p. 4
ISSN
1748-717X

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
47029241
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
COMPUTER CODES; POPULATIONS; THERAPY
Descriptors DEC
MEDICINE

Optional Information

Copyright
Copyright (c) 2007 Niyazi et al
Notes
PMCID: PMC1770926; PUBLISHER-ID: 1748-717X-2-4; PMID: 17212832; OAI: oai:pubmedcentral.nih.gov:1770926; licensee BioMed Central Ltd.