The field theory of symmetrical layered electrolytic systems and the thermal Casimir effect

We present a general extension of a field-theoretic approach developed in earlier papers to the calculation of the free energy of symmetrically layered electrolytic systems which is based on the sine-Gordon field theory for the Coulomb gas. The method is to construct the partition function in terms of the Feynman evolution kernel in the Euclidean time variable associated with the coordinate normal to the surfaces defining the layered structure. The theory is applicable to cylindrical systems and its development is motivated by the possibility that a static van der Waals or thermal Casimir force could provide an attractive force stabilizing a dielectric tube formed from a lipid bilayer, an example of which is provided by the t-tubules occurring in certain muscle cells. In this context, we apply the theory to the calculation of the thermal Casimir effect for a dielectric tube of radius R and thickness δ formed from such a membrane in water. In a grand canonical approach we find that the leading contribution to the Casimir energy behaves like -kBTLκC/R which gives rise to an attractive force which tends to contract the tube radius. We find that κC∼0.3 for the case of typical lipid membrane t-tubules. We conclude that except in the case of a very soft membrane this force is insufficient to stabilize such tubes against the bending stress which tends to increase the radius. We briefly discuss the role of the lipid membrane reservoir implicit in the approach and whether its nature in biological systems may possibly lead to a stabilizing mechanism for such lipid tubes