Cross section measurements of the 131Xe(p,n) reaction for production of the therapeutic radionuclide 131Cs

131Cs is an X-ray emitter radioisotope gaining interest in prostate brachytherapy. It is generally produced via the 130Ba(n,γ)131Ba→131Cs process in thermal-flux reactors. Here we investigate its cyclotron production possibilities. Excitation function of the 131Xe(p,n)131Cs reaction was measured up to 35 MeV using the stacked gascell technique and high-resolution X-ray spectrometry. The experimental data were compared with results of the ALICE-IPPE and EMPIRE-II codes and curves taken from the PADF and TENDL database. The calculated integral yield was 17 MBq/μA h in the energy range Ep=20→7 MeV. Comparison of cyclotron and reactor production routes was given.