On the Interrelation of Radiation with Malignization Process

A correlation between radiation and malignization processes has been studied It was shown that in some cases radiation may promote development of tumors. Particularly, weak and middle doses appear to be a high high carcinogenic danger. In this article a possible mechanism of malignant transformation of normal somatic cell after exposure of radiation is presented. On the first stage of carcinogenesis after the fusion of cells with perforated plasma membranes, two-nuclei cells appear and then, after caryogamy a mononuclear hybrid cell - precancerous syncaryon was formed. After some conversions on subcellular and molecular levels, this cell may transformed into true cancer syncaryon. (author)