Published 1987 | Version v1
Report Metadata-only

Anatomical and pharmacological comparisons between dopamine D-1 and D-2 receptors in the central nervous system

Creators

Description

Quantitative receptor autoradiography was used to study dopamine D-1 and D-2 receptor subtypes in the central nervous system of several mammals including rats, cats, and monkeys. [3H]-SCH 23390 and [3H]-spiroperidol were used to label the D-1 and D-2 receptors, respectively. Equilibrium binding assays specific for the D-1 and D-2 receptors were characterized using kinetic, saturation, and competition data, along with Scatchard and Hill plots

Availability note (English)

University Microfilms Order No. 88-01,401.

Additional details

Publishing Information

Imprint Pagination
216 p.

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
20048624
Subject category
S60: APPLIED LIFE SCIENCES;
Resource subtype / Literary indicator
Thesis, Non-conventional Literature
Descriptors DEI
AUTORADIOGRAPHY; BIOCHEMICAL REACTION KINETICS; CATS; CENTRAL NERVOUS SYSTEM; COMPARATIVE EVALUATIONS; DOPAMINE; LABELLING; MONKEYS; RATS; RECEPTORS; TRITIUM COMPOUNDS
Descriptors DEC
AMINES; ANIMALS; AROMATICS; AUTONOMIC NERVOUS SYSTEM AGENT; CARDIOTONICS; CARDIOVASCULAR AGENTS; DRUGS; EVALUATION; HYDROGEN COMPOUNDS; HYDROXY COMPOUNDS; KINETICS; MAMMALS; NERVOUS SYSTEM; NEUROREGULATORS; ORGANIC COMPOUNDS; PHENOLS; POLYPHENOLS; PRIMATES; REACTION KINETICS; RODENTS; STEROIDS; SYMPATHOMIMETICS; VERTEBRATES