Published November 1990 | Version v1
Journal article Metadata-only

A model for hematopoietic death in man from irradiation of bone marrow during radioimmunotherapy

Creators

  • 1. Inhalation Toxicology Research Inst., Albuquerque, NM (USA)
  • 2. Johns Hopkins Oncology Center, Baltimore, MD (USA)

Description

The focus of this manuscript is on modelling the risk (or probability) of hematopoietic death in man for exponentially decaying patterns of high-energy β irradiation (e.g. sup (90)/Y) of bone marrow by radioimmunoglobulin injected into the blood. The analytical solutions presented are only applicable f protocols for which significant uptake of radioactivity by the bone marrow does not occur, and only for high energy β emitters. (author)

Additional details

Publishing Information

Journal Title
British Journal of Radiology
Journal Volume
63
Journal Issue
755
Series
Br. J. Radiol.
Journal Page Range
862-870
ISSN
0007-1285
CODEN
BJRAA

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
22022746
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BETA PARTICLES; BLOOD FORMATION; BONE MARROW; CELL KILLING; DEATH; HEMATOPOIETIC SYSTEM; IMMUNOTHERAPY; MAN; MATHEMATICAL MODELS; RADIOTHERAPY; RISK ASSESSMENT
Descriptors DEC
ANIMALS; BODY; CHARGED PARTICLES; IONIZING RADIATIONS; MAMMALS; MEDICINE; ORGANS; PRIMATES; RADIATIONS; THERAPY; TISSUES; VERTEBRATES