Published 2013 | Version v1
Journal article

Piroxicam release kinetics from emulsion microcapsules of low methylated pectin and whey lactoglobulin

  • 1. V.I. Nikitin Institute of Chemistry, Academy of Sciences of the Republic of Tajikistan, Dushanbe (Tajikistan)
  • 2. Tajik State Medical University, Dushanbe (Tajikistan)
  • 3. Eastern Regional Research Center, US Department of Agriculture, Philadelphia(United States)

Description

The study describes release kinetics of piroxicam as model drug from developed two different low methylated-pectins and concentrate of lactoglobulin in condition mimicking gastrointestinal tract. It is shows that the drug release tailored from low methylated-sunflower pectin exhibit zero order kinetics in the condition of intestinal. The results demonstrate effectiveness of microcapsules system as sustained delivery system able to prolong drug release, which may reduce drug dose and its side effect. (author)

Availability note (English)

Available from http://elibrary.ru/

Additional details

Additional titles

Original title (Russian)
Кинетика висвобождения пироксикама из емульсионних микрочастист низкометилированних пектинов и констентрата лактоглобулинов молочноы сиворотки

Identifiers

Publishing Information

Journal Title
Izvestiya Akademii Nauk Tadzhikskoj SSR. Otdelenie Fiziko-Matematicheskikh, Khimicheskikh i Geologicheskikh Nauk
Journal Volume
1
Journal Issue
150
Journal Page Range
p. 89-98
ISSN
0002-3485
CODEN
IATOAN

INIS

Country of Publication
Tajikistan
Country of Input or Organization
Tajikistan
INIS RN
47027780
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Resource subtype / Literary indicator
Numerical Data
Descriptors DEI
CENTRIFUGATION; DIFFUSION; ESTERIFICATION; EXPERIMENTAL DATA; HYDROLYSIS; KINETICS; PECTINS; THERAPY
Descriptors DEC
BLOOD SUBSTITUTES; CARBOHYDRATES; CHEMICAL REACTIONS; DATA; DECOMPOSITION; DRUGS; HEMATOLOGIC AGENTS; INFORMATION; LYSIS; MEDICINE; NUMERICAL DATA; ORGANIC COMPOUNDS; POLYSACCHARIDES; SACCHARIDES; SEPARATION PROCESSES; SOLVOLYSIS