Published October 1981 | Version v1
Journal article

Natural anti-lymphoma activity in C57BL/6 mice: time course of appearance and nature of cytotoxic antibodies

Creators

  • 1. Weizmann Inst. of Science, Rehovoth (Israel). Dept. of Chemical Immunology

Description

A survey of the appearance of natural antibodies in C57BL/6 mice, measured by a complement-dependent cytotoxicity test against syngeneic radiation leukemia virus-induced lymphoma, was performed. Activity could be detected in sera from 5- to 14 month-old animals. This activity could be attributed mainly to IgM antibodies until the age of 10 months, whereas an increasing level of IgG-like antibodies was demonstrated in sera from 12-month-old mice. (Auth.)

Additional details

Publishing Information

Journal Title
Immunol. Lett.
Journal Volume
3
Journal Issue
4
Series
Immunol. Lett.
Journal Page Range
195-198
ISSN
0165-2478