Published March 1981 | Version v1
Journal article Metadata-only

Position-specific radioiodination utilizing an aryltributylstannyl intermediate

Creators

  • 1. Harvard Medical School, Boston, MA (USA)
  • 2. Northeastern Univ., Boston, MA (USA)

Description

An isotopically substituted, iodinated derivative of the antiestrogen tamoxifen is produced utilizing a novel aryltributylstannyl intermediate. Methods of introducing the radioiodine are explored. Potential generality of this method for labeling of other aromatic organic molecules is discussed. (author)

Additional details

Additional titles

Subtitle (English)
Synthesis of "1"2"5I-iodotamoxifen

Publishing Information

Journal Title
Int. J. Appl. Radiat. Isot.
Journal Volume
32
Journal Issue
3
Series
Int. J. Appl. Radiat. Isot.
Journal Page Range
171-173
ISSN
0020-708X

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
12606907
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
CHEMICAL PREPARATION; ESTROGENS; IODINATION; IODINE 125; LABELLED COMPOUNDS; ORGANIC IODINE COMPOUNDS
Descriptors DEC
BETA DECAY RADIOISOTOPES; CHEMICAL REACTIONS; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; HALOGENATION; HORMONES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; RADIOISOTOPES; STEROID HORMONES; SYNTHESIS