Effectiveness of different CT-guided percutaneous biopsies for skeletal destructive lesions

Objective: To compare the clinical utility of CT-guided percutaneous biopsies for bone destruction. Methods: The retrospective analysis of pathologic outcomes of 89 cases guided by X-ray and MRI, were obtained by needle aspiration (n=13) of 18-20 G tru-cut biopsy needles (n=22) and 11-13G Ostycut biopsy needles (n=40). Results: Seventy five (84.3%) patients with percutaneous biopsy outcome with concordant results from specimens subsequently obtained at surgery, 14 patients (15.7%) showed pseudo-negative results but no pseudo-positive cases. No obvious differences in pathological results were obtained among these three methods. Conclusions: 1) CT-guided percutaneous biopsy is effective in the evaluation of skeletal destructive lesions; 2) Appropriate selection of percutaneous biopsy method for different kinds of lesion could raise the diagnostic accuracy. (authors)