Published May 1988 | Version v1
Journal article Metadata-only

Simultaneous demonstrations of neuropeptide Y gene expression and peptide storage in single neurons of the human brain

Creators

  • 1. Univ. Hospital, Zuerich (Switzerland)

Description

A combination of in situ hybridization for neuropeptide Y mRNA that used a 32P-labeled complementary RNA probe and immunocytochemistry with polyclonal antibodies against neuropeptide Y were applied to human cortical brain samples to simultaneously localize neuropeptide Y and its mRNA. These two techniques allowed simultaneous identification of neuropeptide Y gene expression and peptide storage in single neutrons of the human brain

Additional details

Publishing Information

Journal Title
Proceedings of the National Academy of Sciences of the United States of America
Journal Volume
85
Journal Issue
9
Series
Proc. Natl. Acad. Sci. U.S.A.
Journal Page Range
3213-3215
ISSN
0027-8424
CODEN
PNASA

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
20063748
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
BRAIN; CYTOCHEMISTRY; GENE REGULATION; HYBRIDIZATION; MESSENGER-RNA; NERVE CELLS; PEPTIDES; PHOSPHORUS 32; TRANSCRIPTION
Descriptors DEC
ANIMAL CELLS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CENTRAL NERVOUS SYSTEM; DAYS LIVING RADIOISOTOPES; ISOTOPES; LIGHT NUCLEI; NERVOUS SYSTEM; NUCLEI; NUCLEIC ACIDS; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANS; PHOSPHORUS ISOTOPES; PROTEINS; RADIOISOTOPES; RNA; SOMATIC CELLS