Published April 1984 | Version v1
Journal article Metadata-only

Biokinetics and metabolism of radiogallium

Creators

  • 1. Gesellschaft fuer Strahlen- und Umweltforschung m.b.H. Muenchen, Neuherberg (Germany, F.R.). Abt. fuer Nuklearbiologie

Description

The large number of publications dealing with biokinetics, metabolism and factors influencing tissue uptake of 67Ga-citrate could not clarify the mechanism responsible for the uptake of this compound into tumor tissue. The present paper reviews biokinetic data obtained from clinical investigations and animal experiments and briefly points out some possible pathways of the mechanism for gallium localisation in tumors as well as in abscesses and inflammatory lesions. (orig.)

Abstract (German)

Zur Biokinetik von Gallium und ueber die Gallium-Anreicherung in Tumoren liegen bereits eine relativ grosse Anzahl von klinischen und tierexperimentellen Untersuchungen vor. Die daraus hervorgegangenen Einzeldaten ergaben bisher jedoch keine endgueltige Klaerung sondern lediglich Hinweise auf die moeglichen Grundmechanismen bei der Anreicherung von Gallium in Tumoren. Die vorliegende Arbeit gibt einen Ueberblick ueber die Biokinetik von Gallium und stellt die moeglichen Anreicherungsmechanismen in Tumorzellen in Kuerze dar. (orig.)

Additional details

Publishing Information

Journal Title
Nuklearmedizin
Journal Volume
23
Journal Issue
2
Series
CODEN: NUKLD.;Nuklearmedizin.
Journal Page Range
53-57
ISSN
0029-5566

Conference

Title
3. international symposium on radiopharmacology.
Dates
21-25 Sep 1983.
Place
Freiburg im Breisgau (Germany, F.R.).

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
15061361
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ABSCESSES; BIOLOGICAL LOCALIZATION; BIOLOGICAL MODELS; CELL CONSTITUENTS; DISTRIBUTION; GALLIUM COMPOUNDS; GALLIUM 67; METABOLISM; NEOPLASMS; RADIONUCLIDE KINETICS; RADIOPHARMACEUTICALS; RATS; TRACER TECHNIQUES
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; GALLIUM ISOTOPES; INFLAMMATION; INTERMEDIATE MASS NUCLEI; ISOTOPE APPLICATIONS; ISOTOPES; KINETICS; LABELLED COMPOUNDS; MAMMALS; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; PATHOLOGICAL CHANGES; RADIOACTIVE MATERIALS; RADIOISOTOPES; RODENTS; VERTEBRATES