Creation of Dosimetric Verification for Implementation of Intensity Modulated Radiation Therapy (IMRT) Validates Using Polymer Gel

Polymer gel dosimeter is a technique that has the ability to map absorbed radiation dose distributions in three dimensions (3D) with high spatial resolution, it offers a number of advantages over traditional dosimeters such as ionization chambers, thermo luminescent dosimeters (TLD) and radiographic film. These gels are reproducible in response and stable 0 n post-irradiation. It is used as the monomer N-iso propyl acryl amide (NIPAM) and N, N- methylene bis acryl amide (Bis) as the cross linker. A historical overview of gel dosimeter was discussed in detail, inside the theses this case; nearly all data met the expected measurement error of 5 % of the maximum dose (50 c Gy). Relative errors were determined to decrease from 25 % at a 2 Gy irradiation to 9.2% for a 10 Gy irradiation The NIPAM polymer gel dosimeter system proved to be an invaluable method for the quantification of the 3-D dose distribution provided by IMRT. A measurement error of less than 5% was achieved. Toxicity and uncertain response to particular environmental characteristics (i.e., temperature and aging) upon the gel are of important concern about the use of the gel at this time. A PAG gel dosimeter is a method verifying dose delivered for prostate cancer radiotherapy treatment, which has been evaluated in this work. A comparison of DVH for PTV between the two treatment plans was verified experimentally. MRI response, the possibility was demonstrated of manufacturing gel dosimeters suitable for 3D dosimeter in the dose range. The results show that IMRT technique not only provides a better conformal dose to the prostate target volume than conventional Seven-field technique, but also reduces doses to the surrounding normal tissues, The aim of this study was to investigate the basic characteristics of the modified gel dosimeter such as temperature effects, magnetic field strength, Ph, aging, energy and dose rate dependence This includes studies of relaxation time dose response, and stability of the measured dose distribution with time. The irradiated gel by linear accelerator after that evaluated by MRI so can also be used to obtain images of the 3-D dose distribution and evaluate dependence of polymer gel dosimeter 1/T₂ on different mean dose rates. Using MRI, the formulation to give the maximum change in the transverse relaxation rate R₂ (1/T₂) was determined when the preparation of final polymer gel solution is completed, the R₂-dose response of the polymer gel dosimeter is linear between 4 to 10 Gy. Dose rate dependence was studied in 6 MV photon beam with the use of dose rates 80, 160, 240, 320, and 400 c Gy/min. Although the treatment time will be extended as more monitor units (MUs) are required to construct the same isocenter dose in the treatment. There are no substantial differences between 6 MV (low) and 10 MV (high) beam energy in treatment planning systems can produce a uniform and considerably equivalent dose plan