Published November 2019 | Version v1
Journal article Metadata-only

Construction of a NT-3 sustained-release system cross-linked with an acellular spinal cord scaffold and its effects on differentiation of cultured bone marrow mesenchymal stem cells

Creators

  • 1. Department of Orthopedics, Xinqiao Hospital, Army Medical University, The Third Military Medical University, Chongqing, 400037, PR (China)

Description

Highlights: • Used EDC to construct the NT-3 cross-linked acellular spinal scaffold. • Sustained-release NT-3 and have biological activity. • Promote the differentiation of bone marrow mesenchymal stem cells. • Potential applications in tissue engineering. -- Abstract: This study sought to promote the adhesion, proliferation and differentiation of rat bone marrow mesenchymal stem cells by constructing a neurotrophin-3 (NT-3) sustained-release system cross-linked with an acellular spinal cord scaffold.

Additional details

Identifiers

DOI
10.1016/j.msec.2019.109902;
PII
S0928493118330364;

Publishing Information

Journal Title
Materials Science and Engineering. C, Biomimetic Materials, Sensors and Systems
Journal Volume
104
Journal Page Range
vp.
ISSN
0928-4931

INIS

Country of Publication
Netherlands
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
55035827
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
BONE MARROW; CELL DIFFERENTIATION; RATS; SPINAL CORD; STEM CELLS
Descriptors DEC
ANIMAL CELLS; ANIMAL TISSUES; ANIMALS; BODY; CENTRAL NERVOUS SYSTEM; HEMATOPOIETIC SYSTEM; MAMMALS; NERVOUS SYSTEM; ORGANS; RODENTS; SOMATIC CELLS; VERTEBRATES

Optional Information

Copyright
Copyright (c) 2019 Published by Elsevier B.V.