Published April 1987
| Version v1
Journal article
Effects of epidermal growth factor on neural crest cells in tissue culture
Description
Epidermal growth factor (EGF) stimulates the release of hyaluronic acid (HA) and chondroitin sulfate proteoglycan (CSPG) from quail trunk neural crest cultures in a dose-dependent fashion. It also promotes the expression of cell-associated heparan sulfate proteoglycan (HSPG) as detected by immunofluorescence and immunoprecipitation of the 3H-labeled proteoglycan. Furthermore, EGF stimulates [3H]thymidine incorporation into total cell DNA. These results raise the possibility that EGF or an analogous growth factor is involved in regulation of neural crest cell morphogenesis
Additional details
Publishing Information
- Journal Title
- Exp. Cell Res.
- Journal Volume
- 169
- Journal Issue
- 2
- Series
- Exp. Cell Res.
- Journal Page Range
- 267-279
- ISSN
- 0014-4827
- CODEN
- ECREA
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 18073117
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Descriptors DEI
- ANIMAL CELLS; BIOCHEMISTRY; BIOSYNTHESIS; CELL CULTURES; CHONDROITIN; DNA; EPIDERMIS; FLUORESCENCE; GLYCOPROTEINS; GROWTH; HYALURONIC ACID; IODINE 125; POLYPEPTIDES; SULFATES; THYMIDINE; TRITIUM COMPOUNDS
- Descriptors DEC
- AMINES; AZINES; BETA DECAY RADIOISOTOPES; BODY; CARBOHYDRATES; CHEMISTRY; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; EMISSION; EPITHELIUM; HETEROCYCLIC COMPOUNDS; HYDROGEN COMPOUNDS; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IODINE ISOTOPES; ISOTOPES; LUMINESCENCE; MUCOPOLYSACCHARIDES; NUCLEI; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; OXYGEN COMPOUNDS; PEPTIDES; PHOTON EMISSION; POLYSACCHARIDES; PROTEINS; PYRIMIDINES; RADIOISOTOPES; RIBOSIDES; SACCHARIDES; SKIN; SULFUR COMPOUNDS; SYNTHESIS; TISSUES