Published May 12, 2004 | Version v1
Journal article Metadata-only

Dynamical Observations of Local Bio-molecular Sites Using Nanocrystals

Creators

  • 1. Sasaki -team, Japan Science and Technology Corporation (JST/CREST), Tachikawa 190-0012 (Japan)
  • 2. Bio-medical Group, SPring-8/Japan Synchrotron Radiation Research Institute, Mikazuki, Hyogo 679-5198 (Japan)
  • 3. Biotechnology Research Center, Teikyo University, Miyamae, Kawasaki 216-0001 (Japan)

Description

Recently, we succeeded time-resolved x-ray observations of picometer-scale slow Brownian motions of individual protein molecules in aqueous solutions. In this work, we investigated the relationship between individual protein molecules and the labeled nanocrystals. In order to control the number of the bonding sites on the labeled gold nanocrystals, we utilized both the periodical structure in Actin filaments and using the mercury compound. As a result, we observed free Brownian Motions of the C-terminal in F-actin, when single gold nanocrystal is linked to single G-actin

Additional details

Identifiers

DOI
10.1063/1.1757971;

Publishing Information

Journal Title
AIP Conference Proceedings
Journal Volume
705
Journal Issue
1
Journal Page Range
p. 1023-1026
ISSN
0094-243X
CODEN
APCPCS

Conference

Title
8. international conference on synchrotron radiation instrumentation
Dates
25-29 Aug 2003
Place
San Francisco, CA (United States)

INIS

Country of Publication
United States
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
36092379
Subject category
S46: INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ACTIN; AQUEOUS SOLUTIONS; BONDING; BROWNIAN MOVEMENT; CONTROL; FILAMENTS; GOLD; MERCURY COMPOUNDS; MOLECULES; NANOSTRUCTURES; PERIODICITY; TIME RESOLUTION; X-RAY DETECTION; X-RAY DIFFRACTION
Descriptors DEC
COHERENT SCATTERING; DETECTION; DIFFRACTION; DISPERSIONS; ELEMENTS; FABRICATION; HOMOGENEOUS MIXTURES; JOINING; METALS; MIXTURES; ORGANIC COMPOUNDS; PROTEINS; RADIATION DETECTION; RESOLUTION; SCATTERING; SOLUTIONS; TIMING PROPERTIES; TRANSITION ELEMENTS; VARIATIONS

Optional Information

Notes
(c) 2004 American Institute of Physics