Methodological and clinical aspects of radionuclide diagnosis of thyroid diseases

A multimodality radionuclide study including thyroscintigraphy, thyroprofilography, radioimmunoassay to determine the levels of thyroid hormones and TSH in the blood serum, and a new method of radionuclide thyrochronoscopy, was conducted in 32 patients with diffuse and nodular enlargement of the thyroid and in 5 patients of the control group. Thyrochronoscopic results were used to determine the percentage of absorption of sup(99m)Tc-pertechnate by the thyroid on the 20th minute, exponential index of absorption and clearance index. Their values turned out elevated in the patients with hyperthyroidism and sUspicion for hyperthyroidism. Three degrees of marked compensatory capabilities of the thyroid tissue were singled out in the patients with the euthyroid status. The study showed the diagnostic value of thyrochronoscopic findings in examining thyroid function. The use of radionuclide thyrochronoscopy enhances the diagnostic efficacy of a comprehensive study of the thyroid