Published May 2015 | Version v1
Journal article Metadata-only

Application of 18F-labeling positron molecular probes in tumor receptor imaging

Creators

  • 1. Key Laboratory of Nuclear Radiation and Nuclear Energy Technology, China Academy of Sciences, Shanghai (China)
  • 2. CAS Center for Excellence TMSR Energy System, Shanghai (China)
  • 3. Department of Radiochemistry and Engineering, Shanghai Institute of Applied Physics, China Academy of Sciences, Shanghai (China)

Description

Tumor receptor imaging characterized by high affinity, high specificity, high selectivity and favorable pharmacokinetic properties, plays a significant role in the diagnosis and staging of tumor. The research progress of 18F labeling positron molecular probes for tumor receptor imaging were reviewed according to tumor receptors which included somatostatin (SST) receptor, vasoactive intestinal polypeptide (VIP) receptor, tumor growth factor receptors, and steroid hormone (SH) receptors. (authors)

Additional details

Publishing Information

Journal Title
Journal of Isotopes
Journal Volume
28
Journal Issue
2
Journal Page Range
p. 121-128
ISSN
1000-7512

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
51032387
Subject category
S07: ISOTOPES AND RADIATION SOURCES; S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
DIAGNOSIS; FLUORINE 18; GROWTH FACTORS; LABELLING; NEOPLASMS; POLYPEPTIDES; POSITRONS; PROBES; RECEPTORS; SOMATOSTATIN; SPECIFICITY
Descriptors DEC
ANTILEPTONS; ANTIMATTER; ANTIPARTICLES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; DISEASES; ELEMENTARY PARTICLES; FERMIONS; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LEPTONS; LIGHT NUCLEI; MATTER; MEMBRANE PROTEINS; MITOGENS; NANOSECONDS LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; PEPTIDES; PROTEINS; RADIOISOTOPES

Optional Information

Notes
4 figs., 48 refs.