Published 1991
| Version v1
Journal article
Molecular target size of the vanilloid (capsaicin) receptor in pig dorsal root ganglia
Description
The size of the vanilloid receptor was examined by high-energy radiation inactivation analysis of the binding of [3H]resiniferatoxin to pig dorsal root ganglion membranes; it was found to be 270 ± 25 kDa. This value most likely represents the size of a receptor complex rather than of an individual subunit. Other ligand-gated cation channel complexes have reported molecular weights in this range, e.g. 300 kDa for the acetylcholine receptor
Additional details
Publishing Information
- Journal Title
- Life Sciences
- Journal Volume
- 48
- Journal Issue
- 19
- Series
- Life Sci.
- Journal Page Range
- 1863-1869
- ISSN
- 0024-3205
- CODEN
- LIFSA
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 22055294
- Subject category
- S60: APPLIED LIFE SCIENCES; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOCHEMICAL REACTION KINETICS; CAPSICUM; CELL MEMBRANES; CHEMICAL COMPOSITION; IONIZING RADIATIONS; MOLECULAR WEIGHT; NERVE CELLS; PROTEINS; RECEPTORS; SWINE; TOXINS; TRACER TECHNIQUES; TRITIUM COMPOUNDS
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; ANTIGENS; CELL CONSTITUENTS; DOMESTIC ANIMALS; HYDROGEN COMPOUNDS; ISOTOPE APPLICATIONS; KINETICS; MAMMALS; MEMBRANES; ORGANIC COMPOUNDS; PLANTS; RADIATIONS; REACTION KINETICS; SOMATIC CELLS; VERTEBRATES