Radiopharmaceutical absorbed dose considerations

From the discussion in this chapter the reader may get the impression that absorbed dose calculations are primarily guesswork. Admittedly, assumptions must be made in some calculations when there are gaps in the available data. These calculations, however, represent an estimate of the true absorbed dose with reasonably sufficient accuracy to assure the physician and regulatory agencies that patients are not receiving excessively high absorbed radiation doses. The MIRD technique appears to be an acceptable method of dose calculations, with individual calculations being only as good as the input information. All possible situations have not been modeled, nor will they ever be, but absorbed dose estimation can continue to be of use with application of available data, some common sense, and a few reasonable assumptions