Published July 1984
| Version v1
Journal article
On the mechanism of synergistic carocinogenic effect of radiation and other agents: role of mutation and activation of oncogenes and genes which control the growth factor synthesis
Description
A hypothesis is proposed on the role in the radiation carcinogenesis of mutation and (or) activation of combination of the several prooncogenes, some of which are homologous of the growth factors or probably to the actin. The antibodies to the products of oncogenes may be used to study mechanisms of carcinogenic action of radiation and other factors or even as diagnostic tool or remedy
Additional details
Additional titles
- Original title (Russian)
- О механизмах синергизма при комбинированном канцерогенном де ствии излучений и других факторов: рол' мутации и активации онкогенов и генов, контролирующих синтез ростовых факторов
Publishing Information
- Journal Title
- Radiobiologiya
- Journal Volume
- 24
- Journal Issue
- 4
- Series
- Radiobiologiya.
- Journal Page Range
- 569-571
- ISSN
- 0033-8192
INIS
- Country of Publication
- Russian Federation
- Country of Input or Organization
- USSR
- INIS RN
- 16030348
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL EFFECTS; CARCINOGENESIS; DNA; GENES; IONIZING RADIATIONS; MAMMALS; MUTATIONS; NEOPLASMS; SYNERGISM; TUMOR CELLS
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; DISEASES; NUCLEIC ACIDS; ORGANIC COMPOUNDS; PATHOGENESIS; RADIATIONS; VERTEBRATES