Published 1989
| Version v1
Book
Carbon-11 labelling by malonic ester synthesis
Creators
- 1. Kitasato University (Japan). Department of Hygienic Sciences
Description
Conditions in the malonic ester synthesis for various α-(11C-methyl)-carboxylic acids including 11CH3CH2CO2H were studied especially in view of rapidity and ease. The labelling provided to usually proceed fairly rapidly in a good yield. Also, 11CH3CH2CO2H was synthesized as an example of preparing (β-11C-ethyl)-ketones from β-diketones or acylacetic esters and 11CH3I. Some of the products are effectively used, together with corresponding 14C compounds, in metabolic studies by double tracer method. (author). 3 refs.; 1 fig.; 1 tab
Additional details
Publishing Information
- Publisher
- Elsevier.
- Imprint Place
- Amsterdam (Netherlands)
- ISBN
- 0-444-87368-6
- Imprint Title
- Synthesis and applications of isotopically labelled compounds 1988
- Imprint Pagination
- 860 p.
- Journal Page Range
- p. 633-636.
Conference
- Title
- International symposium on the synthesis and applications of isotopically labelled compounds.
- Dates
- 17-21 Jul 1988.
- Place
- Innsbruck (Austria).
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- Netherlands
- INIS RN
- 22049793
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- CARBON 11; CARBOXYLIC ACID ESTERS; CARBOXYLIC ACIDS; LABELLING; MALONIC ACID
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBON ISOTOPES; DICARBOXYLIC ACIDS; ESTERS; EVEN-ODD NUCLEI; ISOTOPES; LIGHT NUCLEI; MINUTES LIVING RADIOISOTOPES; NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; RADIOISOTOPES
Optional Information
- Notes
- Imprint:Includes author index and subject index.