Published September 1994 | Version v1
Journal article Metadata-only

Target model of nucleosome particle for track structure calculations and DNA damage modelling

Creators

  • 1. Ceskoslovenska Akademie Ved, Prague (Czech Republic). Ustav Radiologicke Dozimetrie
  • 2. Ceske Vysoke Uceni Technicke, Prague (Czech Republic). Fakulta Jaderna a Fysikalne Inzenyrska

Description

A non-homogeneous target model of nucleosome particle for track structure calculations and biophysical modelling of radiation-induced DNA damage was developed together with a sampling method for non-homogeneous targets. The model allows one to distinguish energy deposited in the histone core, primary hydration shell and nucleosome DNA. Illustrative results for low energy electrons are presented and compared with results obtained with simpler models of a nucleosome particle. (author)

Additional details

Publishing Information

Journal Title
International Journal of Radiation Biology
Journal Volume
66
Journal Issue
3
Journal Page Range
p. 267-277.
ISSN
0955-3002
CODEN
IJRBE7

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
26005471
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; COMPUTERIZED SIMULATION; DNA; ENERGY DEPOSITION; NUCLEOSOMES; PARTICLE TRACKS
Descriptors DEC
BIOLOGICAL EFFECTS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RADIATION EFFECTS; SIMULATION