Published September 1990 | Version v1
Journal article Metadata-only

Measurement of renal blood flow by 131I-labelled sodium iodohippurate imaging in a rat model of herpes encephalitis

Creators

  • 1. Manchester Univ. (UK). Dept. of Medical Biophysics
  • 2. Manchester Univ. (UK). Dept. of Medical Microbiology

Description

Renal blood flow was assessed qualitatively over a 30 min period in a rat model of herpes encephalitis by extra-renal scintigraphic imaging following the injection of 131I-labelled sodium iodohippurate. No significant differences were observed for renal blood flow in either kidney between (or within) infected and control groups. Our data suggest that kidney function is not compromised in this animal model of encephalitis. The results are discussed in the context of the development of a non-invasive protocol for the in vivo diagnosis of herpes encephalitis. (orig.)

Additional details

Publishing Information

Journal Title
Acta Radiologica
Journal Volume
31
Journal Issue
5
Series
Acta Radiol.
Journal Page Range
538-539
ISSN
0284-1851
CODEN
ACRAE

INIS

Country of Publication
Sweden
Country of Input or Organization
Denmark
INIS RN
22028480
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BLOOD FLOW; ENCEPHALITIS; HERPES SIMPLEX; HIPPURAN; IODINE 131; KIDNEYS; LABELLED COMPOUNDS; MEASURING METHODS; RATS; RENAL CLEARANCE; TRACER TECHNIQUES
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CLEARANCE; CONTRAST MEDIA; DAYS LIVING RADIOISOTOPES; DISEASES; EXCRETION; INFECTIOUS DISEASES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; NERVOUS SYSTEM DISEASES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPES; RODENTS; SKIN DISEASES; VERTEBRATES; VIRAL DISEASES