Published December 1981
| Version v1
Journal article
Micro analysis of myocardial lipids after administration of radioiodinated fatty acids
Creators
- 1. Bonn Univ. (Germany, F.R.). Inst. fuer Klinische und Experimentelle Nuklearmedizin
Description
Radioactivity distribution in rat hearts was determined after i. v. bolus application of ω-123I-heptadecanoic acid. Significant radioactivity uptake was found in myocardial lipids 1 min. p. i.. Radioactivity incorporation into intermediary products of myocardial lipid metabolism was analysed by means of a modified microlipid analysis firstly described by EGGE. Definite radioactivity uptake into phospholipids, triglycerides, cholesterol as well as into free fatty acid fraction was observed. This method therefore renders possible investigation of radioiodinated free fatty acid myocardial intermediary metabolism. (orig.)
Abstract (German)
Nach i. v. Bolusapplikation von ω-123J-Heptadecansaeure wurde die Radioaktivitaetsverteilung im Rattenherzen untersucht. 1 Minute p. i. fand sich ein signifikanter Radioaktivitaets-Uptake in myokardialen Lipiden. Mit einer modifizierten Mikrolipidanalyse nach EGGE wurde die Radioaktivitaetsinkorporation in Intermediaerprodukte des Lipidstoffwechsels analysiert. Ein definierter Radioaktivitaetseinbau konnte in Phospholipiden, Triglyceriden und Cholesterin sowie in der freien Fettsaeurefraktion nachgewiesen werden. Das beschriebene Verfahren der Mikrolipidanalyse stellt ein wertvolles Hilfsmittel zur Untersuchung des Intermediaerstoffwechsels radioiodinierter Fettsaeuren in Warmblueterherzen dar. (orig.)Additional details
Additional titles
- Original title (German)
- Mikro-Lipidanalyse von Herzmuskelgewebe nach intravenoeser Applikation von radiojodinierten Fettsaeuren
Publishing Information
- Journal Title
- Nuc Compact
- Journal Volume
- 12
- Journal Issue
- 6
- Series
- Nuc Compact.
- Journal Page Range
- 280-282
- ISSN
- 0344-3752
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 13684235
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- AUTORADIOGRAPHY; DECANOIC ACID; DIAGNOSIS; INTRAVENOUS INJECTION; IODINE 123; LIPIDS; METABOLISM; MYOCARDIUM; RATS; THIN-LAYER CHROMATOGRAPHY; TISSUES; UPTAKE
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; CARDIOVASCULAR SYSTEM; CHROMATOGRAPHY; ELECTRON CAPTURE RADIOISOTOPES; HEART; HOURS LIVING RADIOISOTOPES; INJECTION; INTAKE; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; MAMMALS; MONOCARBOXYLIC ACIDS; MUSCLES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPES; RODENTS; SEPARATION PROCESSES; VERTEBRATES