Published April 1997 | Version v1
Journal article

A case of infantile Dubin-Johnson syndrome with high CT attenuation in the liver

  • 1. Department of Pediatrics, Juntendo University School of Medicine, Tokyo (Japan)

Description

We report a case of Dubin-Johnson syndrome (DJS) with severe infantile cholestasis and elevated computed tomography (CT) attenuation of the liver. Increased levels of urinary coproporphyrin I were found as well as pigment granules in the hepatocytes and hepatosteatosis. The CT attenuation was markedly higher in the liver of this patient at the ages of 3 and 7 months than in the spleen or kidneys. This high attenuation may be a finding specific to infantile DJS and, therefore, abdominal CT may be helpful in the diagnosis. (orig.). With 3 figs

Additional details

Publishing Information

Journal Title
Pediatric Radiology
Journal Volume
27
Journal Issue
4
Journal Page Range
p. 345-347.
ISSN
0301-0449
CODEN
PDRYA5

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
28045366
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
COMPUTERIZED TOMOGRAPHY; INFANTS; JAUNDICE; LIVER; METABOLIC DISEASES
Descriptors DEC
ANIMALS; BODY; CHILDREN; DIGESTIVE SYSTEM; DISEASES; GLANDS; MAMMALS; MAN; ORGANS; PATHOLOGICAL CHANGES; PRIMATES; SYMPTOMS; TOMOGRAPHY; VERTEBRATES