Published May 2008 | Version v1
Journal article

Sprout Branching of Tumour Capillary Network Growth: Fractal Dimension and Multifractal Structure

  • 1. Institute of Condensed Matter Physics, Zhejiang Normal University, Jinhua 321004 (China)

Description

A tumour vascular network, characterized as an irregularly stochastic growth, is different from the normal vascular network. We systematically analyse the dependence of the branching. It is found that anastomosis of tumour on time is according to a number of tumour images, and both the fractal dimensions and multifractal spectra of the tumours are obtained. In the cases studied, the fractal dimensions of the tumour vascular network increase with time and the multifractal spectrum not only rises entirely but also shifts right. In addition, the best drug delivery stage is discussed according to the difference of the singularity exponent δα(δα = αmax — αmin), which shows some change in the growth process of the tumour vascular network. A common underlying principle is obtained from our analysis along with previous results. (fundamental areas of phenomenology (including applications))

Availability note (English)

Available from http://dx.doi.org/10.1088/0256-307X/25/5/061

Additional details

Identifiers

Publishing Information

Journal Title
Chinese Physics Letters
Journal Volume
25
Journal Issue
5
Journal Page Range
p. 1746-1749
ISSN
0256-307X
CODEN
CPLEEU

INIS

Country of Publication
China
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
44125069
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE; S60: APPLIED LIFE SCIENCES;
Descriptors DEI
ANTINEOPLASTIC DRUGS; BLOOD VESSELS; CAPILLARIES; FRACTALS; IMAGES; NEOPLASMS; STOCHASTIC PROCESSES; TIME DEPENDENCE; VASCULAR DISEASES
Descriptors DEC
BLOOD VESSELS; BODY; CARDIOVASCULAR DISEASES; CARDIOVASCULAR SYSTEM; DISEASES; DRUGS; ORGANS