Published March 1981
| Version v1
Journal article
The potentiation of ozone toxicity by thyroxine
Creators
Description
In the presence of thyroxine, human erythrocytes exposed to ozone exhibit enhanced osmotic fragility and the association of radio-activity from 125I-labeled thyroxine with the major membrane glycoprotein, glycophorin. These events are accompanied by enhanced cation permeability in the absence of either measurable inhibition of ATPase activity or membrane lipid peroxidation. It is suggested that the thyroid hormones may play a role in the expression of ozone toxicity
Additional details
Publishing Information
- Journal Title
- Res. Commun. Chem. Pathol. Pharmacol.
- Journal Volume
- 31
- Journal Issue
- 3
- Series
- Res. Commun. Chem. Pathol. Pharmacol.
- Journal Page Range
- 483-492
- ISSN
- 0034-5164
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 13699351
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- ATP-ASE; BIOLOGICAL EFFECTS; CELL MEMBRANES; ERYTHROCYTES; GLYCOPROTEINS; IODINE 125; LUNGS; OZONE; SENSITIVITY; THYROID; THYROXINE; TOXICITY; TRACER TECHNIQUES
- Descriptors DEC
- AMINO ACIDS; BETA DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; CARBOHYDRATES; CARBOXYLIC ACIDS; CELL CONSTITUENTS; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; ENDOCRINE GLANDS; ENZYMES; ESTERASES; GLANDS; HORMONES; HYDROLASES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MEMBRANES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANS; PEPTIDE HORMONES; PHOSPHATASES; PROTEINS; RADIOISOTOPES; RESPIRATORY SYSTEM; SACCHARIDES; THYROID HORMONES