Published September 1988 | Version v1
Journal article Metadata-only

Differential diagnosis of solitary pulmonary nodules with positron emission tomography using [11C]L-methionine

Creators

  • 1. Tohoku Univ., Sendai (Japan)

Description

Two patients with solitary pulmonary nodules, 1.5-2.0 cm in diameter, were studied by positron emission tomography using [11C-Methyl]L-methionine (11C-Met). Case 1 showed high accumulation of 11C-Met in the tumor, and a tumor/muscle ratio of 6.0 suggesting malignancy. Tissue obtained by biopsy revealed a squamous cell carcinoma. Case 2 showed nonspecific isotope accumulation in the tumor, and a tumor/muscle ratio of 1.2 suggesting a benign lesion. Lung biopsy demonstrated granuloma. Positron emission tomography with 11C-Met seems to be useful for the differential diagnosis of solitary lung nodules

Additional details

Publishing Information

Journal Title
Journal of Computer Assisted Tomography
Journal Volume
12
Journal Issue
5
Series
J. Comput. Assist. Tomogr.
Journal Page Range
794-796
ISSN
0363-8715
CODEN
JCATD

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
20026621
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BIOPSY; CARBON 11; CARCINOMAS; DIAGNOSIS; LUNGS; METHIONINE; PATIENTS; POSITRON COMPUTED TOMOGRAPHY
Descriptors DEC
AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; CARBON ISOTOPES; CARBOXYLIC ACIDS; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; EVEN-ODD NUCLEI; ISOTOPES; LIGHT NUCLEI; LIPOTROPIC FACTORS; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC SULFUR COMPOUNDS; ORGANS; RADIOISOTOPES; RESPIRATORY SYSTEM; TOMOGRAPHY