Treatment of the pigmented villonodular synovitis with the colloid of P-32

Objective: To analyze the value of colloid P-32 in the treatment of Pigmented villonodular synovitis (PVS). Method: 12 cases of knee PVS received the treatment with colloid P-32. After drawing the fluid from the joint cavity, the colloid of P-32 5mCi was injected into the cavity then the patients were asked to lie down 40 min, and to change position every 10 min. Blood routine was examined before and once a week after the therapy in the first month and then once a month in the following 6 months. 22 cases received operation. All the patients were follow-up. Result There is no side re- action and the blood routine was normal in the follow-up. The cure rate was 100% in colloid P-32 treatment group. However, 7 cases of PVS recurred and the cure rate was 68.2% in operation treatment group. Conclusion: The injection of P-32 colloid in the cavity of knee joint to treat the PVS is safety and effective. (authors)