Multi-mode Sample Introduction System (MSIS) as an interface between high performance liquid chromatography (HPLC) and inductively coupled plasma optical emission spectrometry (ICP OES) in arsenic speciation analysis

The usage of a commercial in–spray chamber hydride generator, Multi–mode Sample Introduction System (MSIS) as an interface between high performance liquid chromatography and inductively coupled plasma optical emission spectrometry (HPLC–MSIS–ICP OES) is presented. The optimization of hydride generation in MSIS and chromatographic run (using anion–exchange HPLC column with phosphate buffer as a mobile phase) were carried out compositely. Within 400 s of a single analysis, the method allowed to determine three arsenic forms: As(III), As(V) and dimethylarsinate (DMA) with satisfying limits of detection (2.1–7.0 μg L–1) and precision (2.7–5.7%). Recovery for standard addition method was high and acceptable (95–106%). The described method was used for environmental and food samples analyses. Besides of the mentioned hyphenated technique, perspectives of other optical systems are presented. Full results were presented in Proch & Niedzielski, Talanta, 208 (2020) 120395 and Proch & Niedzielski, Analytica Chimica Acta, 1147 (2021), 1–14.