Application of model systems in nanobiotechnology safety

Full text : Last 10-15 years the human civilization, as a result of fast development of biotechnology, cases of new and known illnesses and increase of danger of bioterrorism, collides with new biological dangers. Now, all necessity of actions for biology for prevention of possible dangers admits. Nanobiotechnological researches and offers on application of the scientific results reached in this area prevail of all others. And thus, in many cases or it is at all left outside of attention possible harmful effects of application in an expert of nanoparticles, or it is limited to researches on subcellular level. Adequate results can be received only in case of carrying out of such researches on organism level. Greater prospects in this area have the model systems consisting the culture of unicellular green seaweed, on which now we have been studying the ionizing radiation influence effects. It speaks that on behalf of such cultures we have simultaneously cellular, organism and population levels of the structural organization. Some optimal laboratory methods of maintenance and propagating of this unicellular green seaweed have already been developed. The way offered was a studying at cellular-organism level of the structural organization of effects of action on vital systems of nanoparticles (especially what are offered for application in pharmaceutics) with use of culture of unicellular green seaweed Chlamydomonas reinhardti. Genes of many enzymes of this eucariotic seaweed are established, and also its perspective value in biological synthesis of hydrogen is shown. Studying of negative effects of action of nanoparticles in an example of the object, many molecular features of which are investigated, will allow to establish borders of safety of all biosystems.