Published August 2005 | Version v1
Journal article Metadata-only

Thrombolytic efficacy of rt-PA in embolic stroke of rabbits by 99Tcm trace

Creators

  • 1. Institute of Radiation Medicine, Chinese Academy of Medical Science and Beijing Union Medical College, Tianjin (China)

Description

It is established that rabbit model of embolic stroke by injecting its thrombus into internal carotid. The therapy effect of recombinant tissue plasminogen activator (rt-PT) is studied by 99Tcm trace. The results indicate that the thrombolytic efficacy of rt-PA is potent when the rabbit model of embolic stroke treated is with 0.5, 1 mg/kg rt-PA. (authors)

Additional details

Publishing Information

Journal Title
Journal of Isotopes
Journal Volume
18
Journal Issue
3
Journal Page Range
p. 160-163
ISSN
1000-7512

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
37110776
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BRAIN; EMBOLI; PLASMINOGEN; RABBITS; TECHNETIUM 99; THERAPY; THROMBOSIS; TRACER TECHNIQUES
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BLOOD COAGULATION FACTORS; BODY; CARDIOVASCULAR DISEASES; CENTRAL NERVOUS SYSTEM; DISEASES; DRUGS; FIBRINOLYTIC AGENTS; HEMATOLOGIC AGENTS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; MEDICINE; NERVOUS SYSTEM; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; PROTEINS; RADIOISOTOPES; TECHNETIUM ISOTOPES; VASCULAR DISEASES; VERTEBRATES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
2 figs., 9 refs.