Published January 1989 | Version v1
Journal article

Labelling of ochratoxins with 3H or 125I

  • 1. Ceskoslovenska Akademie Ved, Prague (Czechoslovakia). Ustav Nuklearni Biologie a Radiochemie
  • 2. Institut Hygieny a Epidemiologie, Prague (Czechoslovakia)
  • 3. Slovak Academy of Sciences, Prague (Czechoslovakia). Inst. of Microbiology

Description

Catalytic hydrogenation of ochratoxin A by carrier-free tritium was used to prepare 3H-ochratoxin B with a high specific activity. Iodination of ochratoxin B by carrier-free Na 125I using the chloramine method yielded 125I-ochratoxin with a high specific activity. Another 125I-derivative of ochratoxin A was prepared by iodination of an ochratoxin A - L-tyrosine-methylester conjugate. All three radioactive preparations were found to be useful for radioimmunoassay. (author)

Additional details

Publishing Information

Journal Title
Journal of Labelled Compounds and Radiopharmaceuticals
Journal Volume
27
Journal Issue
1
Series
J. Labelled Compd. Radiopharm.
Journal Page Range
51-57
ISSN
0362-4803
CODEN
JLCRD